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Author Topic: The northern hemisphere is under threat by a deadly disease moving to humans.  (Read 354 times)

ama

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The northern hemisphere is under threat by a deadly disease moving to humans. This means the entire destruction of THE BASE of human settlements lasting thousands of years. No food, no humans. Eskimos, Lapps, Siberians, Indians, all the native population loses the key of its nutrition.

Hunters and gatherers depend on a clean nature.

It is gone.



Many, many, many, embedded urls in the text. This copy here only is an anchor. Do go to the original web-page and read there!

http://www.environews.tv/081517-venison-elk-may-no-longer-safe-eat-study-deadly-chronic-wasting-disease-moving-humans/

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EnviroNews | The Environmental News Specialists dc news bureau
Local EnviroNews

HEALTH ADVISORY: Venison, Elk May No Longer Be Safe to Eat — Study: Deadly Chronic Wasting Disease Could be Moving to Humans

    bureau EnviroNews DC News Bureau by Dan Zukowski on August 15, 2017 Leave a comment   

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(EnviroNews DC News Bureau) — Alberta, Canada — Early results from an ongoing study testing human susceptibility to chronic wasting disease (CWD), a growing epidemic among deer and elk, has led Health Canada to warn “that CWD has the potential to infect humans.”

Chronic wasting disease is an incurable, inevitably fatal illness that can affect all cervids: deer, elk, moose and caribou. It is one of several prion diseases (pronounced pree-on), of which the most well-known is mad cow disease, or bovine spongiform encephalopathy (BSE). The Centers for Disease Control (CDC) identifies six known animal prion diseases and five that affect humans. The most common prion illness in people is Creutzfeldt-Jakob disease (CJD).

In an advisory dated April 26, 2017, Health Canada cited a research project led by Dr. Stefanie Czub, head of the virology section at the Canadian Food Inspection Agency (CFIA), using cynomolgus macaques (Macaca cynomolgus). These primates are the closest to humans that can be used in medical research. “These findings suggest that CWD, under specific experimental conditions, has the potential to cross the human species barrier, including by enteral [oral] feeding of CWD infected muscle,” the advisory stated.

“The shockwaves are still reverberating through the scientific community because of this research,” said Darrel Rowledge, Director of the Alliance for Public Wildlife (APW), in a lengthy interview with EnviroNews. A former forester, Rowledge calls himself an activist and has been studying chronic wasting disease for almost 20 years. He’s visited the lab where the CFIA study is underway. “This is a wakeup call. These macaque data are stunning.”
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Prions are abnormal, misfolded proteins. Lacking cell nuclei, they are not alive like bacteria, though they behave much like parasitic life forms as they replicate themselves by hijacking and misfolding otherwise normal proteins in the unfortunate host. They cause diseases that are collectively called transmissible spongiform encephalopathies, or TSEs. Such diseases commonly infect the brain and spinal cord, and are nearly always undetectable until symptoms arise, often years or even decades after infection.

CWD was first identified in Colorado in the 1960s and has since spread to 24 states and two provinces in Canada. Small outbreaks have also occurred in South Korea and Norway.

Spongiform Encephalopathy: Brain of the First Reindeer to Test Positive for CWD in Norway

It has long been believed that CWD is unlikely to infect humans due to the presence of a so-called “species barrier.” But BSE was also considered to be cordoned off until 1996 when Great Britain admitted, after years of denial, that mad cow disease had been transmitted to humans. Worldwide, 229 deaths have been reported. Those people were infected by eating meat or organs from disease-ridden cattle.

Previous studies on chronic wasting disease have hinted at the possibility of transmission to humans, leading the World Health Organization (WHO) to recommend in 2012 that no “part or product of any animal which has shown signs of a TSE should enter the (human or animal) food chain.” Recent controlled laboratory studies have shown that other mammals can be infected with CWD. These include mice, voles, and squirrel monkeys. A 2012 study by researchers at Colorado State University found domestic cats susceptible to CWD infection.

“There’s always been a suspicion of the possibility, a hypothetical risk of transmission to humans,” Dr. Ryan Maddox, an epidemiologist with the CDC, told EnviroNews. “It’s something CDC has been keeping an eye on for a number of years.” But the new CFIA study adds further concern.

Begun in 2009, Czub started with 21 macaques, all females two and a half years old. Three were designated as negative controls while 18 were infected, or “challenged,” as scientists prefer to say, with CWD. Five were infected orally, two through the skin and nine directly into the brain. Three animals received intravenous injection of blood from other CWD-challenged macaques. Of the 21 animals, 10 are dead so far, including one of the three control specimens, which was euthanized for purposes of the study.

As some of these macaques became sick, they developed anxiety and tremors. Researchers reported that they began to lose control of their bodily movements. Four of the animals began wasting away, with one having lost one-third of its body weight in less than six months. Post-mortems and other tests have been completed on five macaques so far. Under the microscope, the tissue samples showed damage typical of malformed prion proteins, primarily in the spinal cord and brain.
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Cynomolgus Macaques Used for Research

“We felt that these results should be communicated,” Czub told EnviroNews in a detailed phone interview. “It teaches us really something about the species barrier.” She explained that BSE, or mad cow disease, showed up mainly in the spinal cords of macaques during earlier experiments, “and it seems to be the same in chronic wasting disease.”

What most surprised the researchers was the short length of time it took for some of these test animals to show signs of disease. The earliest onset was four and a half years — the same amount of time that cynomolgus macaques need to develop infection from BSE. “It should have taken longer for CWD,” Czub said.

Dr. Stefanie Czub

One of only six experts certified by the World Organization for Animal Health to head a BSE Reference Laboratory, Czub was born in Marburg, Germany to parents who were both veterinarians. She earned her doctoral degree in Berlin where she first became involved in researching prion diseases. Czub gained more experience in the field at the National Institute of Health in Montana. In addition to her position at the CFIA, she teaches at the University of Calgary and has published many papers on prion diseases.

While most scientists would wait for the completion of their study and then submit the results to a peer-reviewed journal, Czub and her colleagues felt they couldn’t wait. “This whole experiment was done to generate data for a risk assessment of chronic wasting disease, and a risk assessment is always to protect human health,” Czub explained. “What we have so far is important enough to communicate it.”

The information was presented to the Canadian health authorities by the Alberta Prion Institute, which is funding the study. Health Canada, an organization described as “responsible for helping Canadians maintain and improve their health,” responded with its risk advisory.

EnviroNews asked the Public Health Agency of Canada, a separate arm of the Ministry of Health, for its response. In an email reply, Anna Maddison, Senior Media Relations Advisor, stated, “Initial results from a Canadian-led research project suggest that chronic wasting disease (CWD) is transmissible to non-human primates, specifically macaque monkeys. Although these findings are scientifically significant, the implications for human risk are not yet clear. The study is ongoing, and the final results must still be subjected to formal expert peer review.”

Rowledge demurred. “There is clearly a disconnect between policy and science,” he said. “We have been, at a fundamental level, ignoring some of the basic rules of science and epidemiology for years.”

A 2017 whitepaper published by the APW explains, “Prions are extremely resilient, known to resist disinfectants, alcohol, formaldehyde, detergents, protein enzymes, desiccation, radiation, freezing, and incineration [at greater than] 1100°F.” The paper, now being revised in light of Czub’s findings, was co-authored by Rowledge along with experts from the University of Calgary, the Wisconsin Natural Resources Board and Canada’s National Wildlife Disease Strategy.

Students at Montana State University Test a Deer for Chronic Wasting Disease

“CWD is very, very challenging,” Czub sighed. According to the APW whitepaper, chronic wasting disease now represents “the largest bio-mass of infectious prions in global history.”

“This is not just an issue that matters to people who care about wildlife,” Rowledge added. “This matters to everyone.” That’s because approximately 75 percent of new human pathogens in the past 25 years have originated in animals, according to a 2009 British study. That study goes on to note, “Greater risks to human health from wildlife pathogens appear to be inevitable as a consequence of increasing human contact with wildlife through greater access to, and disturbance of, wildlife habitats.”

CWD is believed to have originated in Colorado, likely in mule deer (Odocoileus hemionus) in the 1960s. It has expanded both geographically and to other cervids through exportation of infected herd animals, the environment and even through plants. Where deer or elk are highly concentrated, the infection can spread rapidly. A 2004 study by the University of Nebraska-Lincoln found that CWD migrated to Canada from the U.S. through a game farm in Saskatchewan. The disease spread from there to other game farms and to animals living in the wild. Game farms, artificial feeding and baiting encourage the spread of chronic wasting disease.

Captive Elk Cow With Chronic Wasting Disease — Photo: Terry Kreeger — For: Wyoming Game and Fish

The Alliance for Public Wildlife estimates that 7,000-15,000 CWD-infected animals are consumed in North America each year. Rowledge explained they derived that figure through statistical analysis of deer populations in infected areas, the prevalence of infection and the number of animals harvested by hunters. But he cautioned that as state governments have cut back on testing, lack of hard data makes precise numbers difficult.

Testing of deer and elk kills is mostly voluntary, and usually comes at the request of hunters only when they suspect a diseased animal – typically from signs such as drooling or emaciation. “It’s not just that we don’t have enough precautionary measures to stop people from eating [these animals]; it’s that we’ve failed fundamentally to follow science and evidence in terms of containing the epidemic,” Rowledge said.

Deer Drooling with Chronic Wasting Disease

In the U.S., Colorado, Wyoming and Wisconsin are considered the hotspots for chronic wasting disease. According to Colorado Parks and Wildlife, one in every three elk and one in two deer are known to be infected with chronic wasting disease. This year, the state instituted mandatory testing in some areas.

Wyoming is in danger of losing its entire deer population to CWD. A 2016 University of Wyoming (UW) study of white-tailed deer (Odocoileus virginianus) herds in the state, published in Plos ONE, found a 10 percent annual decline in the population of these herds, with the likelihood they would be wiped out in less than 50 years.

At least three cases of CWD-infected deer have been reported in Pennsylvania this year. In Wisconsin, one in eight deer in a single CWD-prone area tested positive in 2016. More than 65,000 animals killed in that region went unexamined, while testing in the state as a whole declined from 30,272 animals in 2002 to 6,129 in 2016.

Extracting a Deer Lymph node for CWD Testing — Photo: Tom Carlson — For: Wisconsin Department of Natural Resources

Hunters, it seems, are more likely to kill infected deer. The UW study found that CWD-positive animals were over-represented in the harvest, possibly because infected animals change their behavior and react more slowly. But those subtle changes may not be apparent to the hunter, leading them to skip testing and possibly consume tainted meat.

“This is where it becomes really concerning for human health,” said Czub. “The muscle tissue we used [in our experiment] was from white-tailed deer, from a farm population in Saskatchewan and those animals did not show clinical signs [of CWD].” They would have appeared healthy to the average hunter.

Most states downplay the risks to people with statements like the one published in a pamphlet for hunters by the Wyoming Game and Fish Department that reads: “There is currently no evidence that CWD is transmitted to humans.” Colorado states: “Currently, there is no evidence that CWD poses a risk for humans; however, public health officials recommend that humans avoid exposure to CWD prions.” The Wisconsin Bureau of Wildlife Management website reads, “There is no strong evidence that chronic wasting disease (CWD) can be passed to humans.”

David Edmunds Testing for CWD Through Tonsil Biopsy — Photo: Todd Cornish

The World Health Organization, in an overview of prion illnesses, says, “No human case has been linked so far to these animal diseases.” The CDC, on its web page about CWD, states, “To date, no strong evidence of CWD transmission to humans has been reported.” The written response we received from the Public Health Agency of Canada echoes the same line: “At this time, there is no direct evidence to suggest that CWD may be transmitted to humans.” These organizations all recommend that hunters take precautionary measures when handling their kills and have suspected animals tested. But that may not be enough.

Diseased animals can harbor CWD prions for years without showing any signs. There is no diagnostic test short of a post-mortem to detect infected specimens. “A singular event can become a massive problem,” warned Rowledge. “In the case of BSE [mad cow disease] going to people, it was extremely unlikely, but 229 people lost that lottery.”

“At this point our recommendation is for hunters to strongly consider testing in situations where they may be hunting in an area where CWD has been identified in the cervid population,” said Ryan Maddox of the CDC, adding, “We’re looking into how we might revise that in the future.”

Of particular concern are indigenous populations who may rely on wild game for a large portion of their meat protein. Authorities in Canada contacted First Nations immediately following the release of the CFIA study data.

But what if you don’t hunt and don’t eat venison or elk? Can CWD still find its way into your home?

In 2009, researchers in Wisconsin watched 40 deer carcasses and 10 gut piles to see which scavengers took an interest. There was a surprising find: “Domestic dogs, cats, and cows either scavenged or visited carcass sites, which could lead to human exposure to CWD,” stated the study published in the Journal of Wildlife Management. Cats were shown to be susceptible to chronic wasting disease in a separate 2013 study published in the Journal of Virology. These researchers concluded “that the ingestion of and/or open wound exposure to CWD-contaminated material could cause feline TSE disease.”

What you feed your cat or dog might be worrisome too. Pet food contains “meat by-products” which, according to PetMD, can include diseased livestock. A 2013 investigation by Slate found that zoo animals, euthanized shelter animals and road kill all go to rendering plants, where they are ground up, cooked and then sold to pet food manufacturers. More than one million deer are killed in vehicle collisions in the U.S. each year. Wyoming, a known hotspot for CWD, made the top-10 list of states where a driver is most likely to strike a deer, according to insurance industry statistics. At these rendering plants, large cookers heat the raw ingredients to between 250 and 275 degrees for 90 to 180 minutes, according to an EPA document. But prions are known to resist destruction at temperatures four times that high.

Deer antler velvet, which the CDC found to contain chronic wasting disease prions, is now a popular nutritional supplement. It’s being used as a performance enhancer by athletes, and sellers claim it promotes muscle strength, energy and endurance. Dr. Andrew Weil, a practitioner of integrative medicine, writes, “I know of no scientific evidence to support any of the marketing claims made for these supplements.” The CDC warned, “Our studies indicate that antler velvet represents an additional source for human exposure to CWD prions.”

9-Year-Old Boy Poses With CWD-Positive Deer

All of these avenues of possible exposure worry Rowledge. “We have to stop the movement of live animals, we have to stop the movement of product, we have to stop the movement of equipment from these game farms, we have to stop hunters from moving positive animals out of CWD areas.”

Both Canadian and U.S. authorities say they are taking steps to look for any indication that chronic wasting disease may have spread to humans in any form. So far, they’ve seen none. Maddison wrote to EnviroNews, “The Public Health Agency of Canada, in collaboration with Canadian health professionals and healthcare institutions, conducts ongoing national surveillance for all human prion diseases in Canada.”

Maddox explained that the CDC works with the National Prion Disease Pathology Surveillance Center at Case Western Reserve University to review “unusual cases” of human prion disease. Autopsies are performed and brain tissue examined. They look at cases from Colorado and Wyoming, where CWD has been endemic for decades. They also examine younger prion disease victims because the most common human prion disease, CJD, shows up primarily in older adults. Any similar disease in younger patients would raise a red flag. Aware of Czub’s new findings, Maddox said, “We’re paying close attention to this study and keeping track of what’s going on in the human population in this country as far as prion diseases go.”

There are caveats to Czub’s research, which she freely admitted. It is in-progress research, and the complete results will not be in for a few years. The study won’t be published in a peer-reviewed science journal until then. Additionally, two of the macaques in her study had diabetes, which Czub explained, lowers the level of insulin in the animal. Insulin is known to have a protective effect on neurons in the brain, thus potentially making them more susceptible to infectious prions.

But her study, which is funded at least through 2018, raises important questions about the potential for chronic wasting disease to show up in humans. She told EnviroNews that the scientific community may be overestimating the strength of the species barrier. “It’s something which I think we will need to be really dealing with.”

Rowledge was more blunt. “I don’t know what part of this isn’t a disaster unless we get in front of it.”

OTHER REPORTS ON PRION DISEASE BY ENVIRONEWS:

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Alberta Prion Institute, Alliance for Public Wildlife, Andrew Weil, Animal Rights, Animals, Anna Maddison, Antler Velvet, APW, Bovine Spongiform Encephalopathy, BSE, Canadian First Nations, Canadian Food Inspection Agency, Canadian Ministry of Health, Caribou, Case Western Reserve University, Case Western Reserve University National Prion Disease Pathology Surveillance Center, Cat, Cats, Cattle, CDC, Centers for Disease Control, Centers for Disease Control and Prevention, Cervid, Cervidae, Cervids, CFIA, Chronic Wasting Disease, CJD, Colorado Parks and Wildlife, Cows, Creutzfeldt-Jakob Disease, CWD, Cynomolgus Macaque, Cynomolgus Macaques, Dan Zukowski, Darrel Rowledge, Deer, Deer Antler Velvet, Deer Elk and Moose Wasting Disease, Deer Hunting, Dr. Andrew Weil, Elk, Elk Hunting, Enviro News, EnviroNews, Environment, Environmental News, Feline, Feline TSE Disease, Felines, First Nations, Health Canada, Hunting, Journal of Virology, Journal of Wildlife Management, Livestock, Mad Cow, Mad Cow Disease, Mice, Moose, Moose Hunting, Mule Deer, National Institute of Health, National Prion Disease Pathology Surveillance Center, National Wildlife Disease Strategy, Nature and Wildlife, Odocoileus hemionus, Odocoileus virginianus, PetMD, Prion, Prions, Public Health Agency of Canada, Ryan Maddox, Species Barrier, Squirrel Monkey, Squirrel Monkeys, Stefanie Czub, Transmissible Spongiform Encephalopathy, TSE, University of Calgary, University of Nebraska-Lincoln, University of Wyoming, Venison, Voles, White-Tailed Deer, WHO, Wisconsin Bureau of Wildlife Management, Wisconsin Natural Resources Board, World Health Organization, World Organization for Animal Health, Wyoming Game and Fish Department
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    Meet The New GMO Mosquito — Millions Carrying the ‘Kill Switch Gene’ Already Released
    Six Tiny Island Countries To Sue Big Oil For Disrupting the Climate
    More Earthquakes Rattle Alberta — Experts, Regulators Say Fracking to Blame
    Massive New Study Claims Link Between Parental Age and Autism
    America’s First Grid-Connected Wave Energy Conversion Project Comes Online
    PA Residents ‘Terrified’ After Williams Transco Natural Gas Pipeline Ruptures — Resistance Mounting
    Living Things’ Edible Blue-Green Algae Lights Illuminate & Heat Building Simultaneously
    Feds Trying to Force-Feed More Toxic Fat-Free Flavored Milk to School Kids Nationwide
    To ‘poo or not to ‘poo? That Is The Question — No Shampoo Movement on the Rise in America
    Arizona’s GOP Senators Sell Off Apache Burial Grounds to Rio Tinto With Sneaky NDAA Land-Grab Rider
    World’s Last N. White Rhino Male Remains Under Armed Guard — Now, Can Scientists Save the Species?
    Petition Seeks to Pressure Quaker and Pepsi Co. Into Supporting GMO Labeling
    Over 5,000 Protest in Twin Cities at Historic ‘Tar Sands Resistance March’
    More Bans on Fracking Bans as ALEC-Driven State Power-Grabs Over Local Oil & Gas Rules Continue
    Group Files Legal Petition to Stop the Use of Sterility-Inducing Pesticide PZP on Wild Horses
    South African Medical Waste Incinerator Crushes Community Under Deadly Black Smoke
    Maryland’s GOP Governor Lets Fracking Moratorium Stand
    PETITION WATCH: Petition Seeks to Pressure Johnson & Johnson to Stop All Animal Testing
    Denton Protesters in Showdown With Big Oil Over Ban on Fracking Bans — 6 Arrested
    BLM Approves Carbon Bomb Bigger Than KXL: More Wyoming Coal — Lots More
    Study Shows Minnesota Rivers and Lakes Littered with Chemicals, Pharmaceutical Drugs
    ‘Monarch Wings Across Ohio’ Campaign Launches with Aggressive Effort to Save the Species
    Drone Footage Shows Devastating Scope of Deforestation for Palm Oil in Indonesia
    USA Freedom Act Doesn’t Go Far Enough to Stop Government Spying, Critics Say
    New U.S. DOE Breakthrough Could Simplify Tokamak Design for Fusion Energy
    Norway’s $900bn Behemoth ‘Oil Fund’ to Divest $4.5bn from Coal
    Burt’s Bees Spearheads Coalition to Save America’s Honeybees
    Sri Lanka’s President Bans Monsanto Roundup and all Glyphosate Products
    Edinburgh University Caves to Campaign Pressure, Divestment in Coal, Tar Sands Coming
    Petition Demands DOJ Investigation of Koch Brothers for Perpetrating Voter Fraud
    LiveLeak Video: Bull Takes Savage Revenge, Terrifies Arena, Mauls Rodeo Clown, Bull Riders
    Coal India, World’s Largest Coal Producer, Scraps 37 Mines Due to Plummeting Solar Prices
    Graphic Video: Dog Boiled Alive in Wok on Chinese Streets, as Amused Onlookers Laugh
    Trial Begins for Ex-TEPCO Chairman, Two VPs, for Death of 44 People in Fukushima Meltdowns
    Historic First: Solar Plant Illuminates Syrian Refugee Camp, Vastly Improving Quality of Life
    1st Solar Panels Sprout at Chernobyl as Ukraine Seeks Investments to Solarize Exclusion Zone
    Petition Watch: ‘Stop Poisoning Bald Eagles With Toxic Lead’ Nearing First Signature Milestone
    ‘Conservation Success’: Once ‘Extinct’ Scimitar-Horned Oryx Returned to the Wild in N. Africa
    Signable Petition Demands Zinke to Reject HJR 69, Trump’s Bear Cub/Wolf Pup Killing Bill
    World’s 1st Stem Cell Transplant from Donor to Man’s Eye Shows Promise of Restoring Sight
    Want Some Salt With Your Plastic? — Study: 17 of 17 Sea Salt Brands Littered With Petrochemicals
    Germany Converts Coal Mine into Giant Battery to Store Renewable Energy for off-Hours
    Mind-Blowing Video: Python Sliced Open After Swallowing Man Whole in Indonesia
    Drone Video: Giant, Critically Endangered Leatherback Sea Turtle Swims Through Sand Back to Sea
    Up Yours! Revenge: Mexican Matador Gored up the Butt With 11 Inches of Bull Horn
    Denmark Killin’ It With Wind Power, Leading the Way on Climate (While Trump Wants More Coal)
    Amazing Video: French Military Training Golden Eagles to Take Out Drones
    Nuclear Hogs: Radioactive Wild Boars Running Amok Around Fukushima; Hunters Deployed

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Nature and Wildlife

    HEALTH ADVISORY: Venison, Elk May No Longer Be Safe to Eat — Study: Deadly Chronic Wasting Disease Could be Moving to Humans
    Defenders of Wildlife Announces New Satellite Data Program to Track Wildlife Habitat Loss
    Watch: Ever Seen an American White Pelican Walk on Water? (Video)
    Watch: Ever Seen an American White Pelican Walk on Water? (Video)

EnviroKids

    Many Kids Received More Plastic Than Candy or Eggs This Easter
    Many Kids Received More Plastic Than Candy or Eggs This Easter
    EnviroKids: Shelly the Snail — What she’s been doing in your garden
    EnviroKids: Shelly the Snail — What she’s been doing in your garden
    Families Camp Out in Protest to Save the Tavaputs Plateau from America’s First Approved Commercial Tar Sands Mine
    Families Camp Out in Protest to Save the Tavaputs Plateau from America’s First Approved Commercial Tar Sands Mine

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